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MIGRAINE HEADACHES

Do you or does someone you know suffer from Migraine Headaches? You are not alone!

Migraine Symptoms May Include

  • Aura
  • Light sensitivity
  • Sound sensitivity
  • Moderate to severe pain on one side of the head
  • Vision changes, blurred vision
  • Nausea
  • Vomiting

Migraine headaches can cause an intense pulsing or throbbing sensation in one area of the head. They are often accompanied by extreme sensitivity to sound and light, along with nausea and vomiting.

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The pain caused by migraine headaches can be severe and can last for hours or days with no relief.

Some migraines are preceded by an aura (sensory warning symptoms), such as tingling in the arms and legs, flashes of light or blind spots.

Sometimes, finding a dark, quiet place to lay down may alleviate some of the symptoms associated with migraine headaches. Medications can also be prescribed.

Again, nearly 30 million Americans suffer from migraine headaches. Women are 3 times more likely to suffer from them than men. Medical researchers have not yet identified what causes migraines, but family history does play a significant role.

Are you (or someone you know) experiencing any of the symptoms listed above? If so, you may be interested in enrolling in a clinical research study to determine if a newly developed investigational medication for Migraine Headaches at Axiom Research is effective for you. If you are interested, please contact us and our experienced staff will discuss the research study with you. As a participant, you will receive physician visits and study medication at no cost. You do not need insurance and may be compensated for your time and travel expenses.

Alzheimer's Disease

Do you believe that you or someone you know may be suffering from Alzheimer's Disease? You are not alone!

Alzheimer's disease is a progressive, degenerative disorder. Scientists believe that for most people, Alzheimer's disease is caused by a combination of environmental, genetic and lifestyle factors that affect the brain over time. The disease attacks the brain's nerve cells (neurons), damaging and killing them, resulting in loss of memory, behavioral changes and loss of thinking and language skills.

Alzheimer's disease is not a normal part of aging. But increasing age is the greatest known risk factor for the disease. It is the most common cause of dementia (loss of intellectual function) among people aged 65 and older.

Currently, there is no known cure for Alzheimer’s Disease, but medical treatments may improve the quality of life for those suffering with the disease.

Alzheimer's Disease Symptoms May Include

  • Increasing forgetfulness/mild confusion
  • Memory loss
  • Difficulty organizing thoughts/remembering things
  • May repeat statements/questions over and over
  • May forget conversations/appointments or events
  • May routinely misplace possessions
  • May get lost in a familiar place
  • May forget names of family members and everyday objects
  • May have trouble finding words to express thoughts/converse
  • Difficulty with thinking/reasoning
  • Difficulty with multi-tasking
  • Difficulty responding to everyday problems
  • Difficulty planning and performing familiar tasks
  • Changes in personality or behavior
  • Depression, apathy, social withdrawal, mood swings, distrust in others, irritability and aggressiveness, changes in sleep habits, wandering, loss of inhibitions and/or delusions.
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Are you (or someone you know) experiencing several of the symptoms listed above? If so, you may be interested in enrolling in a research study, to determine if a newly developed investigational medication for Alzheimer’s Disease at Axiom Research is effective for you. If you're interested, please contact us and our experienced staff will discuss the research study with you. As a participant, you will receive physician visits and study medication at no cost. You do not need insurance and may be compensated for your time and travel expenses.

Depression

Do you or someone you know suffer from depression? You are not alone! Depression affect more than 15 million Americans every year.

All of us will experience sadness at some point during our lives. Though sometimes painful, the sadness often subsides with time and does not interfere with daily life. Every year, 15 million American adults are affected by Major Depressive Disorder (MDD), a common, but serious medical illness. Major Depressive Disorder does interfere with daily life. Those suffering from it may be disrupted in their ability to eat, sleep and work, and in their ability to enjoy things that were once pleasurable. Normal functioning is disrupted, causing distress for the person with MDD and for those around them.

Symptoms of Depression May Include

  • Feelings of sadness, hopelessness, emptiness or tearfulness
  • Feeling tired/lacking energy
  • Feelings of worthlessness or guilt, fixating on past failures, putting undue blame upon yourself
  • Anxiety, agitation or restlessness
  • Loss of interest or pleasure in most or all normal activities (e.g., sex, hobbies or sports)
  • Angry outbursts, irritability or frustration (even over small matters)
  • Sleep disturbances (insomnia or over sleeping)
  • Changes in appetite — often reduced appetite and weight loss, but sometimes increased cravings for food and weight gain
  • Slowed thinking, speaking or body movements
  • Trouble thinking, concentrating, making decisions and/or remembering things
  • Unexplained physical problems, such as back pain or headaches
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For many people with depression, symptoms usually are severe enough to cause noticeable disruption in their relationships with others. Day to day activities (i.e., work, school and social activities) become problematic. Other people may feel unhappy/generally miserable without really knowing why.

Are you (or someone you know) experiencing any of the symptoms listed above? If so, you may be interested in enrolling in a clinical research study to determine if a newly developed investigational medication for Depression at Axiom Research is effective for you. If you're interested, please contact us and our experienced staff will discuss the research study with you. As a participant, you will receive physician visits and study medication at no cost. You do not need insurance and may be compensated for your time and travel expenses.

OBSESSIVE COMPULSIVE DISORDER

Do you or does someone you know suffer from Obsessive Compulsive Disorder? You are not alone!

OCD SYMPTOMS MAY INCLUDE

Obsession Symptoms:

  • Persistent, repeated and unwanted thoughts, images or urges
  • These thoughts, images or urges are intrusive, typically when a person is attempting to do or think about other things
  • These thoughts, images or urges cause distress or anxiety
  • Obsessive symptoms are often a) ignored or b)attempted to be dismissed by performing a compulsive ritual or behavior.

Common Obsessive Themes Include:

  • Fear of dirt/contamination
  • Doubting (e.g., that you’ve locked the door or turned off the stove)
  • Difficulty tolerating uncertainty
  • Requiring everything to be orderly/symmetrical (intense stress if not)
  • Disturbing thoughts -- harming self/others/aggression/religion/sexually inappropriate

Compulsion Symptoms:

  • Repetitive behaviors that a person feels driven to perform
  • Engaging in behaviors or mental acts meant to reduce anxiety related to obsessions or to prevent something bad from happening.
  • Engaging in compulsions brings no pleasure
  • Engaging in compulsions may offer only temporary relief from anxiety
  • Making up rules/rituals to follow to control anxiety when having obsessive thoughts
  • Compulsions are excessive
  • Compulsions are not related, realistically, to the problem they’re intended to fix

Common Compulsion Themes Include:

  • Washing/Cleaning (e.g., over-washing hands until they’re raw)
  • Checking/Double-Checking (e.g., checking the stove repeatedly to be sure it’s off or checking doors to be sure they’re locked)
  • Counting (e.g., counting in certain patterns)
  • Orderliness
  • Following a strict routine (e.g., repeating the same prayer, word or phrase)
  • Demanding reassurance
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The severity of OCD varies from person to person. OCD usually begins in the young adult and teen years, but it can start as early as childhood. Symptoms usually gradually begin to appear and tend, throughout life, to vary in severity. Types of obsessions and compulsions a person may experience can also change over time. Greater periods of stress tend to generally worsen symptoms. OCD is usually considered a lifetime disorder. A person may experience only mild or moderate symptoms or may have such severe/time-consuming symptoms that it becomes disabling.

Are you (or someone you know) experiencing any of the symptoms listed above? If so, you may be interested in enrolling in a clinical research study to determine if a newly developed investigational medication for Obsessive Compulsive Disorder at Axiom Research is effective for you. If you are interested, please contact us and our experienced staff will discuss the research study with you. As a participant, you will receive physician visits and study medication at no cost. You do not need insurance and may be compensated for your time and travel expenses.

POST TRAUMATIC STRESS DISORDER

Do you or does someone you know suffer from Post Traumatic Stress Disorder? You are not alone!

PTSD SYMPTOMS MAY INCLUDE

  • Being easily frightened or startled
  • Having trouble sleeping - Insomnia
  • Having overwhelming shame or guilt
  • Having trouble concentrating
  • Always being on guard for danger
  • Irritability
  • Hostility
  • Angry outbursts
  • Aggressive Behavior
  • Agitation
  • Experiencing intense, disturbing thoughts and feelings that last long after the traumatic event has ended.
  • Reliving the event through flashbacks or nightmares
  • Feeling sadness, fear or anger
  • Feeling detached or estranged from others
  • Avoiding situations or people that remind them of the traumatic event
  • Strong negative reactions to something ordinary, like a loud noise or an accidental touch
  • Being Hypervigilant
  • Self-destructive behavior or social isolation
  • Severe anxiety or mistrust
  • Loss of interest or pleasure in activities
  • Loneliness
  • Emotional detachment
  • Unwanted thoughts
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BIPOLAR DISORDER

Do you or does someone you know suffer from Bipolar Disorder? You are not alone!

BIPOLAR DISORDER SYMPTOMS MAY INCLUDE

Manic Symptoms:

  • Periods of abnormally elevated mood, energy, or irritability

  • Increased talkativeness or feeling pressured to keep talking

  • Racing thoughts or feeling like your mind won’t slow down

  • Decreased need for sleep (feeling well-rested after only a few hours of sleep)

  • Impulsive or reckless behavior (e.g., excessive spending, risky sexual behavior, fast driving)

  • Inflated self-esteem or grandiosity (believing you have special abilities or powers)

  • Feeling unusually distracted or unable to focus

  • Engaging in excessive goal-directed activities (e.g., overworking, excessive exercise)

Depressive Symptoms:

  • Persistent feelings of sadness, hopelessness, or emptiness

  • Loss of interest or pleasure in activities once enjoyed

  • Fatigue or feeling slowed down

  • Difficulty concentrating or making decisions

  • Changes in sleep patterns (sleeping too much or too little)

  • Changes in appetite or weight (increase or decrease)

  • Feelings of worthlessness or excessive guilt

  • Thoughts of death or suicide

TYPES OF BIPOLAR DISORDER

Bipolar Disorder is classified into different types based on the severity and pattern of mood episodes:

  • Bipolar I Disorder – At least one manic episode, which may be followed by depressive episodes

  • Bipolar II Disorder – Hypomanic episodes (less severe than mania) and major depressive episodes

  • Cyclothymic Disorder – Repeated periods of hypomanic and depressive symptoms that do not meet full criteria for Bipolar I or II

The severity of Bipolar Disorder varies from person to person. The condition often begins in late adolescence or early adulthood, but symptoms can appear at any age. Symptoms tend to fluctuate over time, with some people experiencing long periods of stability between episodes, while others may have frequent and severe mood swings. Stress and major life changes can often trigger or worsen symptoms.

Are you (or someone you know) experiencing any of the symptoms listed above? If so, you may be interested in enrolling in a clinical research study to determine if a newly developed investigational medication for Bipolar Disorder at Axiom Research is effective for you. If you are interested, please contact us and our experienced staff will discuss the research study with you. As a participant, you will receive physician visits and study medication at no cost. You do not need insurance and may be compensated for your time and travel expenses.

METABOLIC DISORDERS

Do you or does someone you know suffer from a Metabolic Disorder? You are not alone!

METABOLIC DISORDER SYMPTOMS MAY INCLUDE

Metabolic disorders occur when the body is unable to properly convert food into energy, leading to imbalances that can affect multiple systems. Symptoms vary depending on the specific condition but may include:

Common Symptoms of Metabolic Disorders:

  • Unexplained weight gain or weight loss

  • Fatigue or chronic lack of energy

  • Difficulty regulating blood sugar levels (high or low blood sugar)

  • High blood pressure or abnormal cholesterol levels

  • Frequent hunger or excessive thirst

  • Difficulty concentrating or brain fog

  • Muscle weakness, cramps, or abnormal pain

  • Digestive issues (nausea, vomiting, bloating, or constipation)

  • Skin conditions such as darkened patches (acanthosis nigricans)

  • Increased risk of infections or slow healing wounds

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COMMON METABOLIC DISORDERS INCLUDE:

  • Diabetes (Type 1 & Type 2) – Impaired insulin production or resistance leading to abnormal blood sugar levels

  • Metabolic Syndrome – A combination of high blood pressure, high blood sugar, excess fat around the waist, and abnormal cholesterol levels

  • Hypothyroidism & Hyperthyroidism – Thyroid disorders that slow down or speed up metabolism

  • Phenylketonuria (PKU) – A genetic disorder affecting protein metabolism

  • Gaucher’s Disease – A disorder that affects how the body processes fats

  • Mitochondrial Disorders – Conditions that affect the body's ability to produce energy at the cellular level

The severity of metabolic disorders varies from person to person. Some conditions develop gradually over time, while others are present from birth. Many metabolic disorders can be managed through diet, lifestyle changes, medication, or specialized treatments, but early detection and intervention are crucial.

Are you (or someone you know) experiencing any of the symptoms listed above? If so, you may be interested in enrolling in a clinical research study to determine if a newly developed investigational medication for Metabolic Disorders at Axiom Research is effective for you. If you are interested, please contact us and our experienced staff will discuss the research study with you. As a participant, you will receive physician visits and study medication at no cost. You do not need insurance and may be compensated for your time and travel expenses.